Saccharomyces boulardii

Common name

Yeast

ID

HD0255

Scientific name of the plant

Saccharomyces cerevisiae CBS 5926

Anatomical part for use

N/A

Human use

Miscellaneous

Summary

Saccharomyces boulardii is a tropical yeast first isolated from lychee and mangosteen fruit in 1923 by French scientist Henri Boulard. Although early reports described distinct taxonomic, metabolic, and genetic properties, S. boulardii is a strain of S. cerevisiae, sharing >99% genomic relatedness, giving the synonym S. cerevisiae var. boulardii.S. boulardii is sometimes used as a probiotic with the purpose of introducing beneficial microbes into the large and small intestines and conferring protection against pathogens. It grows at 37 °C (98.6 °F). In addition, the popular genome-editing tool CRISPR-Cas9 was proven to be effective in S. boulardii. Boulard first isolated this yeast after he observed natives of Southeast Asia chewing on the skin of lychee and mangosteen in an attempt to control the symptoms of cholera. In healthy patients, S. boulardii has been shown to be nonpathogenic and nonsystemic (it remains in the gastrointestinal tract rather than spreading elsewhere in the body).

Evidence Level

Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)

Hepatotoxicity Description

N/A

Relevant Public Information

Wiki
EMA
NIH MedlinePlus
Nature Medicines